At InsAIght, we offer protein design solutions powered by artificial intelligence, tailored to the needs of the pharmaceutical and biotechnology industries.
Our services are divided into three main areas:
- Optimization of proteins to enhance production and manufacturing processes.
- Optimization of protein biological function.
- Development of innovative, patentable proteins.
Optimization of proteins for production and manufacturing
What’s included?
Thermal stability
Proteins designed to withstand elevated temperatures during production and storage, reducing the risk of losing biological activity and extending product shelf life.
Solubility
Enhanced protein solubility in various media, facilitating large-scale manufacturing and improving bioavailability in therapeutic applications.
Reduced protein aggregation
We design proteins with a lower tendency to aggregate, which is a common issue that affects the quality and safety of biopharmaceuticals during production.
Expressibility
Improved expression efficiency in production systems (such as CHO cells or bacteria), increasing yields and reducing manufacturing costs.
Post-translational modifications
Optimization of protein sequences to improve performance in critical modifications, such as glycosylation, which are essential for the manufacturing of biopharmaceuticals.
Our AI platform consists of two key components: StructureGPT, which generates diverse protein sequences, and a suite of AI models that predict various properties and filter the sequences. This allows us to focus on a select number of promising candidates that undergo further experimental validation to confirm the predicted properties.
Who is this service for?
CDMOs
Organizations that require optimized proteins for large-scale production, ensuring efficiency and high yield.
Pharmaceutical and biotechnology companies
Firms focused on the production of biopharmaceuticals that seek to improve the quality and efficiency of their manufacturing processes.
Therapeutic protein manufacturers
Companies producing antibodies, enzymes, and other biopharmaceuticals that need solutions to address issues like stability, solubility, and aggregation during production.
Our value proposition focuses on reducing production times and costs while improving the quality of the final product through the simultaneous optimization of multiple properties. By leveraging our AI-driven platform, we deliver tailored protein solutions that meet the specific manufacturing needs of our clients.
Optimization of biological function
What’s included?
AFFINITY
Optimization of protein sequences to enhance binding affinity with specific targets, improving effectiveness in applications like drug development and diagnostic assays.
SPECIFICITY
Modification of protein sequences to increase binding specificity, reducing off-target interactions and enhancing accuracy in therapeutic and diagnostic applications.
IMMUNOGENICITY
Optimization of protein sequences to minimize immunogenic response, ensuring compatibility in therapeutic applications and reducing the risk of adverse immune reactions.
MOLECULAR INTERACTION
Refinement of protein sequences to improve molecular interactions, enhancing stability and functionality in complex biological systems for advanced research and development.
Who is this service for?
Pharmaceutical and biotechnology companies
Our value proposition centers on enhancing the biological effectiveness and precision of proteins by optimizing critical functional properties, such as affinity, specificity, and immunogenicity. Leveraging our AI-driven platform, we provide customized protein solutions tailored to meet the specific research and therapeutic goals of our clients.
Development of innovative and patentable proteins
What’s included?
Innovative protein design
We introduce structural and functional changes to create entirely new proteins with unique applications in therapeutic areas such as oncology, autoimmune diseases, or rare diseases.
Functional optimization
Our proteins are not only designed for optimal properties such as stability or solubility, but also to fulfill specific therapeutic or technological functions, such as improving antibody affinity for therapeutic targets.
Innovative applications
We collaborate in the development of new therapeutic targets, industrial enzymes, and diagnostic proteins, applying our AI technology to accelerate the discovery process.
Our value proposition focuses on reducing production times and costs while improving the quality of the final product through the simultaneous optimization of multiple properties. By leveraging our AI-driven platform, we deliver tailored protein solutions that meet the specific manufacturing needs of our clients.
Who is this service for?
Pharmaceutical companies with R&D departments
Firms looking to innovate their product pipeline with new proteins that offer competitive advantages and patent potential.
Research centers and universities
Institutions researching biotechnology fields, aiming to develop innovative proteins that can be protected through patents.
Our approach is designed to reduce the time and costs associated with the development of innovative proteins, without sacrificing quality or the degree of innovation. Furthermore, companies can acquire or license the patented proteins, providing flexibility that adapts to their strategic needs.
